Search results for "skin lesions"
showing 6 items of 6 documents
Total body skin examination for skin cancer screening in patients with focused complaints
2012
Background. The value of total body skin examination (TBSE) for skin cancer screening is controversial. Objective: We sought to determine whether TBSE could be helpful in patients with focused skin symptoms who would not otherwise have undergone TBSE. Methods: In a prospective, multicenter, cross-sectional study consecutive adult patients were recruited during a period of 18 months. Physicians first inspected, problem areas and uncovered areas and then performed TBSE. Equivocal lesions detected in both steps were excised or biopsied. Primary outcomes were the absolute and relative risks of missing skin cancer and the number of patients needed to examine to detect melanoma or another maligna…
Depression and Serum Content of Serotonin in Adult Patients with Atopic Dermatitis
2020
Atopic dermatitis (AD) is a chronic skin disease with the etiology not yet conclusively established. Recent reports demonstrate the role of serotonin (5-hydroxytryptamine; 5-HT) in the pathogenesis of AD. The aim of this study was to investigate the relationship between the serum content of serotonin and depression in adult patients suffering from severe AD. There were 31 patients of the median age of 41 years enrolled into the study, who suffered from AD since childhood, and a control group that consisted of 14 healthy subjects. AD was diagnosed on the basis of Hanifin and Rajka criteria. The severity of skin lesions was assessed with the SCORing Atopic Dermatitis (SCORAD) index and that o…
Genetic diversity and phenotypic characterization of Iodobacter limnosediminis associated with skin lesions in freshwater fish
2021
The relatively unknown genus Iodobacter sp. has been repeatedly isolated from skin ulcers and saprolegniosis on freshwater fish in Finland, especially farmed salmonids. Genetic characterization verified that all 23 bacterial isolates studied here belonged to the species Iodobacter limnosediminis, previously undescribed from the fish microbiota. Whole-genome pulsed-field gel electrophoresis revealed variability between the I. limnosediminis strains, suggesting that they were most likely of environmental origin. Two I. limnosediminis strains caused lesions in 27%–53% of brown trout (Salmo trutta) injected intramuscularly (p ≤ .05). The lesions represented moderate to severe tissue damage, but…
Oculoectodermal syndrome: Report of a new case with a broad clinical spectrum
2014
Oculoectodermal syndrome (OMIM 600268) is rare and characterized by aplasia cutis congenita, epibulbar dermoids, and other abnormalities. We report herein on a newly recognized patient with oculoectodermal syndrome, which is the 19th reported patient with OES. The boy aged six years demonstrated a broad clinical spectrum of this condition, including aplasia cutis congenita, epibulbar dermoids, hyperkeratotic papule, mildly enlarged cisterna magna, and an enlarged fluid space in the quadrigeminal cistern, suggesting a cyst. He also manifested anomalies not reported associated with this disorder, including systematized epidermal nevus following Blaschko's lines, hypopigmented skin lesions, an…
Can the lesions induced with actinic keratosis become an enigma for dermatologists? Results of an open perspective study
2017
Different face skin diseases (basal cell carcinoma, actinic keratosis, rosacea, solar elastosis, etc.) could clinically manifest itself as erythematic patches, pimples or plagues. It is very hard to make the clinical exclusion in some cases of these diseases since their characters can partially overlap or certain lesion can mimic another one especially in the cases of skin areas affected with sun. Therefore, the histopathological analysis remains the “golden standard” of the dermatological diagnosis at skin diseases. Our study has shown that certified dermatologists detect actinic keratosis (AK) of face/head skin of I/II levels very well. Verdicts of dermatologists and pathomorfologists are…
Galvenie akūta retrovirāla sindroma simptomi, ādas un gļotādas izpausmes HIV pozitīviem pacientiem korelācijā ar imūnsupresiju un CD4 T šūnu skaitu L…
2018
Ievads: HIV ir viens no visplašāk izplatījiem vīrusu patogēniem pasaulē. Slimības akūtās fāzes izpausmes ir grūti pamanāmas. Pašreizējie pētījumi liecina, ka svaigi inficēti pacienti gūst priekšrocības no agrīnas diagnostikas attiecībā uz slimības gaitu un dzīves pagarināšanu. Tā kā ādas izpausmes ir vienas no visbiežāk sastopamajām, ir svarīgi tās kritiski izvērtēt gadījumā, ja tās parādās citādi veselīga izskata pacientam. Mērķi: Pētījuma mērķis ir analizēt akūtā retrovīrusu sindroma (ARS) galvenos simptomus, lai veicinātu diagnostiku jau akūtas HIV infekcijas laikā, un noteikt, vai pastāv cieša saikne starp noteiktu ādas bojājumu rašanos un CD4 T šūnu skaitu. Materiāli un metodes: pētīju…